Telomeres avoid end detection by severing the checkpoint signal transduction pathway
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چکیده
منابع مشابه
Telomeres avoid checkpoints
Signaling with tortoise and hare indings from Onn Brandman (Stanford University, Stanford, CA) and colleagues suggest that switch-like signal transduction pathways attain speed and reliability by using two positive feedback loops: one fast and one slow. Just one positive feedback loop is enough to create an all-or-none biological switch. Yet many systems, such as yeast polarization, rely on mul...
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ژورنال
عنوان ژورنال: Nature
سال: 2010
ISSN: 0028-0836,1476-4687
DOI: 10.1038/nature09353